3,7-dirhamnoside,Kaempferol 3,7 bisrhamnoside
Molecular Formula :C27H30O14
Boiling Point:908.6 degrees Celsius at 760 mmHg
Flash Point:302.8 degrees Celsius
Vapour pressure: 0mmHg at 25 degrees Celsius
Introduction:kaempferitrin is white crystall oid, dissolving in
methyl alcohol and ethanol alcohol,and drawing up from chinese
thorowax. it's pureness is 60-98%.
Kaempferitrin was found to have an acute lowering effect on blood
glucose in diabetic rats and to stimulate the glucose uptake
percentile, as efficiently as insulin in muscle from normal rats.
This compound did not have any effect on glucosuria or on protein
synthesis in muscle from normal and diabetic animals. However, the
protein synthesis in the kaempferitrin-treated groups was
maintained at the same level as the respective controls. Thus, the
hypoglycaemic effect and the prompt efficiency of the kaempferitrin
in stimulating [U-14C]-2-deoxi-D-glucose uptake in muscle
-constitute the first evidence to indicate that the acute effect of
this compound on blood glucose lowering may occur as a consequence
of the altered intrinsic activity of the glucose transporter (Vmax
or glucose transporters translocation?) not involving directly the
synthesis of new carriers.
It also promotes renal filtration decreases nitrogenimia, increases
the elimination of nitrogen compounds with urine, increases
diuresis and improves sodium and potassium elimination.
Indications: The drug is indicated in cases of renal insufficiency
and nephropathy caused by hyperammoniemia.